What are the Ingredients in Dermisil for Scars?

The active ingredients in Dermisil for Scars are: helichrysum, rosa mosqueta, German chamomile, and lavendula augustifolia.

Medical Study

Anti-inflammatory and antioxidant properties of Helichrysum italicum and other plant extracts.

Sala A, Recio M, Giner RM, Manez S, Tournier H, Schinella G, Rios JL.

Departament de Farmacologia, Facultat de Farmacia, Universitat de Valencia, Spain.

The anti-inflammatory and antioxidant activities of the aerial part of Helichrysum italicum extracts (an active ingredient in Dermisil for Scars) have been established in various in-vivo and in-vitro experimental models. The results obtained on the acute oedemas induced by 12-O-tetradecanoylphorbol 13-acetate (TPA) and ethyl phenylpropiolate in the mouse ear, by serotonin and phospholipase A2 (PLA2) in the mouse paw, on chronic inflammation induced by repeated application of TPA in the mouse ear and on the delayed-type hypersensitivity induced by sheep red blood cells suggest that said anti-inflammatory activity is due to the effects of compounds expressed via a corticoid-like mechanism. In addition, the antioxidant activity of the extracts seems to be implicated in this anti-inflammatory activity, as the former inhibits enzymatic and non-enzymatic lipid peroxidation and has free-radical scavenger properties. We conclude that the anti-inflammatory activity of Helichrysum italicum can be explained by multiple effects, including inflammatory enzyme inhibition, free-radical scavenging activity and corticoid-like effects.

PMID: 11902802 [PubMed - indexed for MEDLINE]